As a Mage, I Only Want to Pursue Truth

A mage accidentally drifts to Blue Star. The intelligent life on Blue Star cannot influence reality by manipulating dark matter, thus the mage loses their casting ability.

In order to recover...

Chapter 128 Qualitative Analysis of the Demon Brain

The above is the answer from an unknown online writer. He wrote a long and detailed explanation, unaware that it was something someone had already thought of.

The Bureau of Abnormal Affairs and the research institutes under its jurisdiction have already conducted relevant experiments.

Creatures cloned from beings with souls also possess souls; however, the hybrids of dogs with souls and dogs without souls exhibit complete randomness.

The only point of value in the anonymous online writer's answer was the presentation of some kind of higher-dimensional matter in the three-dimensional world.

The next day, Qidian transferred 800 yuan to his card, with the note "labor fee". He thought to himself, "I get 800 yuan for just one trip. Qidian, please arrange more of this kind of work for me. I'll take time off to come."

As for why it's 800, anything above 800 would incur personal income tax, so 800 is just right.

......

Wiles asked, "Is it done?"

The nurse beside him replied, "Professor, it's over. You can get up now."

Wiles: "It's tough to have a full physical exam every day."

Every day, we have to do hundreds of tests, from blood draws to X-rays, these are the basics.

Every few days, we need to do some functional tests, including reaction time, intelligence, physical strength, and so on.

Faced with the injection of the magic brain, Wiles could never have imagined that a mathematician who proved Fermat's Last Theorem would one day have to take an intelligence test.

The head of the Brain Research Team is Japanese, which was one of the concessions made by England in order for Wiles to obtain the Brain.

Tasuku Honjo is this Japanese man, the 2018 Nobel Prize laureate in Physiology or Medicine.

As usual, he took Wiles' medical report and looked at it carefully: "Although I have seen Wiles' medical report many times, it always brings me new surprises."

"We need to extract cells from between Wiles' head and neck."

"I suspect that a completely new group of cells has appeared in his cranial nerves."

The assistant beside him replied, "Okay, but I can't guarantee that Professor Wiles won't resist having his blood drawn twice a day."

Tasuku Honjo paused for a moment: "Then let's add this indicator to tomorrow's physical examination."

Wiles held a high position within the base.

Especially when it comes to cooperation between the two countries, Tasuku Honjo hopes to avoid conflict as much as possible.

The next day, the test results were as Honjo Tasuku had expected.

"As expected, new cell clusters appeared in Wiles' cranial nerves."

In normal individuals, cranial nerves originate from only two special cell groups: cranial nerve crest cells and ectodermal basal cell cells.

"But we have no way of determining which signaling pathway changes caused cell differentiation, leading to the appearance of entirely new cell populations in his cranial nerves."

"We originally knew very little about how intercellular signal transduction between neural crest cells and basal cell cells is coordinated during cranial ganglion morphogenesis."

"A new cell population has now appeared in Wiles' cranial nerve, and we need more samples to analyze whether this is a new cell population or multiple cell populations."

Honjo Tasuku muttered to himself.

His assistant stood quietly beside him, waiting for Honjo Tasuku's instructions.

After gathering his thoughts, Tasuku Honjo said, "Could you please find me the paper on Ptch1 loss-of-function mutants? I need to take a look."

The role of Ptch1 functional receptors in regulating Shh signaling during cranial ganglion development.

The Ptch1 Wig/Wig mutant exhibits elevated Shh signaling consistent with trigeminal and facial nerve disorders.

Previous studies have found that enhanced Shh signals inhibit signal transduction in the classic Wnt brain region.

This effect severely impacts the survival and migration of cranial neural crest cells; it also affects the development of basal cell cells and the integration of the neural crest with the basal cell.

Tasuku Honjo hopes to find some inspiration through the experimental design of this paper.

They knew nothing about the Demon Brain, let alone could monitor the microscopic changes within Wiles' body in real time.

There's no way to understand how Wiles gradually acquired the ability to cast spells; we only know afterward what new changes occurred within his body. Nor can we understand how these new changes functioned.

These experiences gave Tasuku Honjo an extremely strong sense of frustration, as if he had returned to his childhood, where everything around him was unknown.

After finishing speaking, Tasuku Honjo continued, "First, we need to determine the types of cell groups in Wiles' body, and second, we need to determine the receptor function of the new cell groups in his body, and how they interact with other nerve tissues, such as the trigeminal nerve and facial nerve."

"Secondly, we need to clone more cells based on the new cell population in his body, and test whether the Ptch1 Wig allele will produce truncated proteins in transfected Hek293T cells by cloning the Ptch1 Wig allele."

“We used an amino(N)-terminus-specific Ptch1 antibody to detect the resulting protein blots to confirm whether the Wig allele of Ptch1 produces a stable truncated form of PTCH1 and to measure its migration.”

"To further evaluate the impact of the Wig mutation on the new cell population level, we performed qPCR experiments using mRNA extracted from cloned cells."

The assistant nodded repeatedly: "Hey!"

Tasuku Honjo waved his hand and said, "I don't know if my design will be useful. In Chinese terms, it's just a desperate measure."

Tasuku Honjo had attempted a similar experiment when new nerve cells appeared in Wiles' body, but he did not find any valuable information.

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