The doctors in the audience couldn't believe their ears.

The clinical treatment of stomach problems has always been a headache for gastroenterologists in the 1980s. Fortunately, China has some classic Chinese medicine prescriptions to nourish the stomach, which can provide some relief.

In the West, doctors know that stomach pain is directly related to excessive secretion of gastric acid, but they have not been able to find a good treatment. At most, they use some alkaline drugs to neutralize it.

This type of treatment is described in Chinese as "treating the symptoms but not the root cause." If you feel pain today, you take some medicine, stop taking it when the pain stops, and continue taking it when the pain comes again. This cycle repeats over and over again, and the problem can never be completely eradicated.

Even ordinary alkaline neutralizing drugs are not very effective, especially for gastric ulcers, there is no particularly good way.

Anyone who has had stomach problems or peptic ulcers knows that when the stomach hurts, the whole body feels uncomfortable.

The most common symptom is sour water in the mouth, and more serious symptoms include radiating pain in the back. This burning pain feels like there is a fire under the xiphoid process.

One of the characteristics of stomach pain is long-term, cyclical, seasonal burning pain that can be triggered or aggravated by meals.

Don’t underestimate stomach pain or long-term excessive secretion of gastric acid, because if the stomach is in an "inflammatory" state for a long time, the tissue cells will begin to degenerate.

Isn’t there a saying: “It starts with inflammation and ends with cancer”?

So when Chen Chun said that their cure rate for Helicobacter pylori had reached 80%, everyone simply couldn't believe their ears.

What does this mean? It means that 90 out of 100 patients with stomach problems have a clear history of Helicobacter pylori infection, and among these 90 people, 72 can be cured and say goodbye to stomach problems forever.

Before this, the mainstream medical community believed that stomach problems could not be cured and could only be treated symptomatically.

Now Chinese doctors suddenly announced that they have mastered a treatment method that can cure most stomach problems. How can this not amaze everyone?

After all, if the Chinese doctor's point of view is correct and the paper confirms it, then all the digestive system textbooks in the world will have to be rewritten.

Jiro Itada of the Tokyo University Medical Hospital stood up, took the microphone, and asked:

"Excuse me, Dr. Chen Chun, what are the principles of your quadruple therapy? Also, excuse me, I've never heard of proton pump inhibitors."

Chen Chun smiled and replied, "I can answer your first question. The second question should be answered by Dr. Zheng Haisheng, the inventor of proton pump inhibitors."

Professor Gregory smiled and said, "Dr. Zheng is also a young doctor. Wow, Chinese doctors are really amazing. This makes me wonder if I am too old."

There was a burst of laughter in the meeting hall.

Zheng Haisheng stood up from his seat with a red face, looking much more nervous. Chen Xia was still shouting beside him, "Brother-in-law, come on! Don't let Chen Chun look down on you. You have to bring honor to us men."

"Okay, I'll tell your sister later that you said that to her."

After saying that, Zheng Haisheng also walked up to the podium and sat next to Chen Chun. Seeing the crowded stage, he swallowed nervously again.

Chen Chun has already started answering the first question:

"Our research has found that Helicobacter pylori is a spiral-shaped, slightly anaerobic bacterium that has very demanding growth conditions. Therefore, the first principle of treatment is the use of antibacterial drugs.

Our multiple drug sensitivity tests have shown that amoxicillin, clarithromycin, furazolidone, metronidazole, tetracycline and other antibacterial drugs are the most effective. Our multiple clinical trials have shown that the best combination is amoxicillin + clarithromycin.

The second treatment principle is to inhibit the secretion of gastric acid. The best medicine now is H2 receptor blocker, but experiments conducted by Xiangjiang Pumpkin Vine Pharmaceutical Company have shown that there is another drug that has a much better acid-suppressing effect than H2 receptor blocker. They named it proton pump inhibitor. Dr. Zheng will introduce the details to you later.

Bismuth is a mucosal protective agent that mainly works by inhibiting the protease, urokinase and phospholipase produced by H. pylori, thereby inhibiting Helicobacter pylori.

These four types of drugs work together to comprehensively eliminate Helicobacter pylori. Of course, we must also be vigilant about the possibility of recurrence, which is another topic: how Helicobacter pylori is transmitted and how to prevent it.

As soon as Chen Chun put down the microphone, the applause became much louder than before. After all, the treatment plan was not based on guesswork, but was completely based on reason and evidence, with research, experiments and clinical comparisons, so it was highly credible.

Zheng Haisheng picked up the microphone and spoke a little haltingly: "I, I will answer the second question."

Chen Chun suddenly kicked him lightly.

This warning from his wife was obviously very effective. Zheng Haisheng had a good mental state and he calmed down instantly. He coughed a few times and continued to answer questions.

"I was commissioned by Xiangjiang Pumpkin Vine Pharmaceutical Company to develop this drug. Regarding its pharmacological effects, it's as follows.

Gastric parietal cells secrete acid by pumping out intracellular H through the H, K-ATPase on the membrane in the form of H-to-K exchange. After the drug is absorbed into the blood, it diffuses into the gastric parietal cells and covalently binds to the HK-ATPase, irreversibly inactivating the pump molecule.

Gastric acid secretion only resumes when new pump molecules are synthesized and inserted into the cell membrane. Therefore, this type of drug has a strong and long-lasting effect in inhibiting gastric acid and can also reduce the secretion of pepsin.

This type of drug acts on the last link of gastric acid secretion, so regardless of whether there are other factors that stimulate gastric acid secretion, this type of drug can effectively inhibit gastric acid secretion..."

When Chen Chun and Zheng Haisheng respectively said the name of "Xiangjiang Pumpkin Vine Pharmaceutical Company", the doctors present were fine, but the representatives of the pharmaceutical companies below the stage remembered the name of the company keenly.

According to international practice, if the research project and drug development are commissioned by a pharmaceutical company, then all the resulting drug patents should be in the hands of the commissioning company.

If this "quadruple therapy" is proven to be reliable and effective, the patents of these drugs will be valuable. You have to know that this is a super large market worth tens of billions of dollars, and even hundreds of billions of dollars in the future.

In the 1980s, the US dollar was still very valuable. Ten billion US dollars was a very remarkable and huge figure, enough to drive these international pharmaceutical giants crazy.

The patents held by this Hong Kong pharmaceutical company that emerged from nowhere will soon become a golden commodity that major pharmaceutical companies will compete for.

Therefore, several pharmaceutical companies that reacted quickly have immediately started investigating this Hong Kong pharmaceutical company.