Jiang Yan's ID on the magic forum is number 2. He has many questions he wants to ask Merlin directly on the forum.
As the administrator behind the forum and the discoverer of magical civilization, Jiang Yan hopes to get answers from Merlin.
"Mr. Jiang, how is the situation on the Magic Forum today? We'll give our routine report, and I'll relay the information back to headquarters later," the staff member asked as he entered the office.
"I can only see my number, which has always been 2 and has never changed. I can't see the total number of numbers."
"There is still only Merlin's single post on the forum, and no one else has posted anything."
"I still haven't figured out how to post. Today's situation is no different from usual."
"The abilities granted by the Demon Brain remain unchanged, and the perception of the seed is still vague."
"Currently, all abilities are in a black box state; they can be used, but the underlying principles cannot be explained."
After Jiang Yan gave a brief report, the staff continued to ask:
"Sir, after reading the 'Zhouyi Cantongqi' and 'Wuzhen Pian,' did your inner demonic mind react in any way? Or did you gain any insights?"
Both "Zhouyi Cantongqi" and "Wuzhenpian" belong to the Taoist practice of internal alchemy. The Bureau of Extraordinary Things specially found a long-standing, extant copy for Jiang Yan to study.
"I have no insights whatsoever. This content is not in the same system as magic at all. I believe that the cultivation methods passed down from ancient times are not the same as the demonic brain."
Due to the emergence of magic, the Bureau of Abnormal Phenomena Investigation not only collected ancient and rare books domestically, but also sent people abroad to collect information related to magic.
Some ancient magic-related artifacts have been sold for exorbitant prices, especially those unearthed in England.
Merlin is an English conjecture, and given that the name Merlin is also associated with a magician in English mythology, English magical artifacts are particularly favored by connoisseurs.
After completing the daily Q&A session, Jiang Yan continued to ponder, finding it strange and even a little funny.
Merlin said in his post that the Magic Forum was created for everyone to communicate and claimed that it was to make everyone realize the value of thinking and to be a platform for communication and value demonstration, but he did not see any communication or exchange.
It's like the group admin saying everyone is welcome to speak, and then setting a mute for everyone.
Jiang Yan was a little puzzled because he had received information that he was not the only person in the world to have obtained the Magic Brain. The Chinese side speculated that Enceladus had been registered and there was at least one Magic Coin in the world.
Currently, there are two theories in China: either the other magic coin hasn't been used yet, or it's possible to post on the magic forum but Jiang Yan hasn't found a way to do so.
Another guess is that another magic coin was used, and the reason why the magic forum cannot post so far is that certain conditions have not been met.
Currently, America and England are closely aligned on the issue of magic, while China has opted for limited information sharing with Russia. There is currently no established mechanism for communication on this topic.
......
“Teacher Jiang, we don’t actually need to select seeds in this way. Seeds selected this way are unlikely to achieve the desired effect and cannot form a sufficient control group.”
“The seeds bred in this way have different mutation points, making it difficult to draw conclusions through control experiments. We cannot publish papers this way,” Dong Wenxu reminded again after another week of breeding.
He continued:
"If you are looking to cultivate genetically modified seeds on a large scale and feel that the current conventional methods are too inefficient, we can use carbon dot spraying for gene editing."
"Carbon dots formed from spherical natural materials with nanoparticles smaller than 10 nm can serve as rapid carriers for carrying plasmids into mature plant cells."
"This leads to the instantaneous plant transformation of many important crops without negatively impacting photosynthesis or growth."
"Introducing GFP, Cas9, and gRNA expression gene fragments into wheat through foliar application (spraying) of plasmid-coated carbon dots, and in the case of Cas9, performing genome editing in the SPO11 gene."
"This spray-on gene editing protocol is simple, inexpensive, and fast, and is applicable to a variety of crops."
"Moreover, it is more targeted, making it easier to conduct control experiments later."
In the subfield of biology that is breeding, the most cutting-edge research methods now involve targeted gene differentiation to study the differences between hypotheses and actual situations.
The mutation rate of herbicide resistance in natural plant populations was studied, and it was examined whether the mutation rate would increase when plants were exposed to sublethal herbicide stress.
Scientists used amaranth and resistance to acetolactate synthase (ALS)-inhibiting herbicides as a model system for discovering spontaneous herbicide-resistant mutants, screening nearly 80 million plants in total.
As for Jiang Yan's research methods, regardless of how far behind the most advanced ones they are, they belong to the research methods of Shennong tasting hundreds of herbs in ancient times.
Jiang Yan knew he needed to do something to stop Dong Wenxu from overthinking: "This method was developed in 2019 by Thomas and his team from Bristol, together with Keith from the Chemistry Department."
“I know this better than you do. The problem with this method is that it cannot guarantee that the gene editing you want will happen.”
"After you spray the rapid carrier, you can't guarantee that it will cause transformation in the plant. In a real experiment, this is a matter of probability. How do you select the seeds that will actually undergo induced differentiation?"
"Isn't it still necessary to go through conventional experiments? This method is not superior to the current mainstream experimental methods. It may seem faster, but that's just your perception."
"The screening process for this method is more complicated than the conventional one."
"If this method were really as superior as Thomas described in his article, you would have seen it being widely adopted at the Agricultural Research Institute long ago."
“I know you don’t believe I can select better seeds based on my intuition, and you think that even if I could select better seeds, I wouldn’t be able to publish a paper with a sufficient impact factor without a reference experiment.”
Dong Wenxu was dumbfounded. He had only read about this method in articles and had never actually tried it, let alone pointed out its disadvantages.
What shocked him even more was that he had indeed read the article and was deeply impressed by it. He brought it up in order to gradually change Jiang Yan's research methods, but he did not expect that the other party would be able to recite the ins and outs of the paper so readily.
They even know the authors of the paper, the university they belong to, and when it was published.
Dong Wenxu murmured, "How can we judge the quality of our work without papers? Besides, if this method really can select better seeds, then is there any need for the science of breeding?"
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