Night fell over the city, neon lights flickering, and the clamor of traffic drifted faintly through the cracks in the windows into the quiet hospital office. Lin Yue, a young and distinguished doctor, sat at a desk piled high with medical files, her brow furrowed, her eyes revealing both fatigue and determination. She had just taken on a patient with an extremely complex condition, a challenge she had never faced before in her medical career.
The patient, Li Hua, was a middle-aged man in his fifties. He was already in a semi-comatose state when he was admitted to the hospital, suffering from a complex combination of unusual symptoms that posed a significant challenge to even the most experienced doctors. Not only did Li Hua suffer from a persistent high fever, hovering around 40°C, but he also developed strange, irregular, and painful red spots all over his skin. Even more worryingly, his liver and kidney function had declined dramatically, with all indicators significantly deviating from normal ranges.
Conventional treatments were ineffective for Li Hua. Lin Yue and her medical team had tried a variety of antibiotics, fever-reducing medications, and supportive care, but Li Hua's condition showed no signs of improvement. Every time she watched Li Hua suffer, Lin Yue felt a wave of guilt and helplessness. She knew that as a doctor, saving lives was her duty, yet now she seemed trapped in an impasse.
Desperate to find a cure for Li Hua, Lin Yue spent days and nights at the hospital. During the day, she monitored Li Hua's condition closely, meticulously recording every subtle symptom. At night, when the hustle and bustle of the hospital subsided, she sat alone in her office, researching reams of medical information. Her desk was piled high with medical books and journals. From classic medical textbooks to the latest research reports, she pored over every possible clue. She meticulously read each article, her eyes glued to every word, hoping for a hint of inspiration. Sometimes, she would be thrilled by a piece of information that might lead to Li Hua's condition, only to discover, upon further research, that it was a false alarm. This sent her spiraling from high to low.
In addition to researching, Lin Yue also actively organized an expert consultation. She invited leading experts from various departments within the hospital, including infectious diseases, dermatology, nephrology, and hepatology, hoping to leverage their expertise and extensive experience to jointly address this medical challenge. The atmosphere in the consultation room was tense and solemn. The experts gathered around the conference table, meticulously examining Li Hua's medical records and various test reports. Each expressed their opinion, but due to the complexity of Li Hua's condition, no consensus was reached.
"Judging from the current symptoms, the patient is likely infected with a rare virus, but our existing testing methods cannot determine the specific virus." Professor Zhang from the infectious disease department said with a frown.
"I think the patient's erythema may be related to the immune system, perhaps caused by some autoimmune disease." Director Wang of the Dermatology Department expressed a different point of view.
"But how do we explain the patient's rapid decline in liver and kidney function? This does not seem consistent with the manifestation of an autoimmune disease." Dr. Liu from the Nephrology Department raised the question.
The experts expressed their opinions, arguing endlessly. Lin Yue listened quietly, her mind churning out various possibilities. She knew that each view had its merits, yet each also held certain unexplained doubts. Amidst this heated discussion, Lin Yue held back from expressing her own opinion, waiting for a spark of inspiration that would connect all the threads.
After several hours of discussion, the consultation ultimately reached no clear conclusion. The experts stated that Li Hua's condition was so rare that they needed more time to study and analyze it. Watching the experts depart, Lin Yue felt a sense of loss. But she didn't give up. She knew that giving up now would mean losing hope for Li Hua's life.
Back in the office, Lin Yue fell into deep thought again. She recalled every detail of Li Hua's hospitalization, trying to find some overlooked clue. Suddenly, she remembered a peculiar symptom from Li Hua's admission—white spots on his oral mucosa. At the time, everyone thought it was just a common oral inflammation, but now it seems that this symptom may be closely related to his overall condition.
Lin Yue immediately turned on her computer and searched medical databases for information on the association between white spots on the oral mucosa and other symptoms. After some effort, she finally found a relevant research report. The report described a rare genetic disease that causes white spots on the oral mucosa, in addition to persistent high fever, erythema, and decreased liver and kidney function. This disease is extremely rare, with only a few cases reported worldwide, and currently no effective treatment exists.
Lin Yue was both excited and worried. She was thrilled to have finally found a clue that closely matched Li Hua's condition; yet she was concerned that the disease, lacking an effective treatment, would only make the challenges she faced even more daunting. But without hesitation, she decided to share her discovery with the medical team and discuss treatment options with them.
At a discussion meeting with the medical team, Lin Yue presented his findings in detail, shocking everyone. This rare genetic disease is not only difficult to diagnose but also extremely challenging to treat. Currently, international research on this disease is still in its infancy, with only a few research institutions conducting clinical trials.
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