Lin Sanqi took a sip of tea and reorganized his words:
"Dean Xiang, my idea is this: your College of Traditional Chinese Medicine should also set up a research team like Professor Tu Youyou's, looking for inspiration from the vast traditional ancient medical books, and then using modern pharmaceutical technology to refine the structure.
If there are any scientific research results, the reputation will belong to your College of Traditional Chinese Medicine or professor team; but all patents will belong to our Lingnan Hall company. Of course, I will also give the project team a generous bonus."
Dean Xiang's eyes sparkled, and he unconsciously moved closer to Lin Sanqi:
"Xiao Qi, this cooperation is great. We have the scientific research capabilities, and you have the financial support. If this model is successful, then our Huadu Medical University School of Traditional Chinese Medicine will definitely become a top-tier institution in the country."
Lin Sanqi wanted to pour some cold water on him at this moment:
"Dean Xiang, in principle, this is the model of cooperation. But I think there are many smart people in the country. Why are there no foundations or large companies willing to take this route to support traditional Chinese medicine research? It must be because this path is too difficult and too expensive, right?"
Nodding slightly to the dean:
"It's very expensive. In the field of pharmaceutical research, there's a 10% rule: if you invest 1 billion and spend 10 years, the success rate is only 10%. It's really very expensive, and the key is that success is not guaranteed.
Domestic companies and chaebols are only focused on short-term profits and don't have the ambition to build century-long businesses. Therefore, they won't invest large sums of money in original drug development. They'd rather buy patented generic drugs and make a quick buck.
Lin Sanqi was very relieved because the old man in front of him was so clear-headed that such cooperation would not fail.
"So, Dean Xiang, my money didn't just come from the wind. If I gave the research funds to your College of Traditional Chinese Medicine, then each professor would form a project team.
Their research project applications were simple, and they desperately tried to squeeze money out of me, regardless of whether the project would ultimately succeed. In the end, I went bankrupt, while they made a killing. So, wouldn't I be the one being taken advantage of?
In the entertainment industry, when director Chen Kexin was filming, he could charge $8,000 for a tattered straw hat. This was a complete scam for investors.
The crew of a certain "Dying to Survive" drama said that a wig would cost more than 200,000 US dollars and had to be custom-made abroad. This is also an act of defrauding investors.
But don’t think that the entertainment industry is disgusting, and don’t think that those university professors are all naive, only care about scientific research, and don’t care about financial gains and losses.
In fact, the worst are these intellectuals. They are very cunning. As long as you dare to delegate power, they will try every possible means to get money out of your pocket.
There are countless academic scandals in universities every year.
For example, 11 students from Huazhong Agricultural University jointly reported Huang Feiruo, a professor in the Department of Animal Nutrition at the university, for academic fraud in a real-name manner.
Professor Huang’s pig farming project alone cost a full 1.8 billion yuan for pig feed, and it is estimated that 1.799 billion yuan was embezzled by Professor Huang.
Just ask you if you are awesome?
Therefore, Lin Sanqi was very worried that most of his scientific research funds would be thrown into the water after being given to this group of intellectuals.
However, intellectuals hold the right to speak in scientific research and are the only tools. Without them, the project cannot be carried out. Therefore, Lin Sanqi is prepared to be ripped off, but hopes not to be ripped off too much.
He doesn't have 1.8 billion to give away.
Dean Xiang also knew the inside story of the scientific research. After all, he was also one of them, so he thought of a way:
"There are actually ways to review and manage scientific research funding. If you trust me, and put the review authority in my hands, I will be a good gatekeeper for you and keep a close eye on it.
In addition, you can entrust a third party to conduct regular financial accounting for the use of funds. For abnormal expenditures, you can kill a few monkeys to make it clear to everyone. Of course, for slightly unreasonable expenditures, you can turn a blind eye.
Lin Sanqi nodded and offered a suggestion:
"Dean Xiang, I think we can also do a composition assignment. Which prescriptions or Chinese herbal medicines have special effects? Then we can specialize in that aspect.
For example, my mom always says celery can open up blood vessels, and she urges us to eat more. So, which ingredient in celery has this blood vessel-opening effect? What is it? Where does it work? That's what we're researching."
Who knew that Dean Xiang suddenly laughed after hearing this:
"Xiao Qi, your intelligence work is out of date. The claim that celery can open up blood vessels actually has a basis. Pharmaceutical companies abroad have already extracted a vasoactive substance, butylphthalide, from celery seeds for the treatment of cerebrovascular disease."
Lin Sanqi slapped his thigh (his hand was about to get swollen from slapping it today):
"Noisy, look to the dean, aren't these all inspirations?"
At this time, Lin Sanqi stood up, walked to Dean Xiang's bookshelf, took a book on Chinese medicine, and opened a page at random.
The Chinese medicine "Chaigui" is written on it.
"Please show me this Chai Gui book. It says:
The bark of Cinnamomum cassia can be used as medicine. It tastes spicy and sweet, is warm in nature, and is slightly toxic. It has the effects of warming the meridians and dispersing cold, promoting qi and blood circulation, and relieving pain. It can be used to treat colds, cold pain in the stomach and abdomen, dysmenorrhea, rheumatic joint pain, trauma, loss of appetite and other symptoms.
So the question is, we know that Chai Gui has these effects, but which specific ingredient is responsible? This is completely worth our research, and it would be best if this active ingredient could be extracted and finally made into a medicine.
Take the simplest example, Xiaoer Chaigui Antipyretic Granules. When my sister and I had a fever, my father liked to use this medicine to treat wind-heat colds, which had the effect of reducing fever and relieving pain.
But the instructions for Xiaoer Chaigui Tuire Granules say: "This product has the effects of diaphoresis, relieving exterior symptoms, clearing the interior and reducing fever. It can be used to treat colds caused by external invasion of wind-heat, invasion of the exterior defenses by pathogens, and loss of pores."
So, the question arises: what are the drug targets for Chaigui Tuifever? What are the lead compounds that interact with these targets? Has research been conducted on the drug's absorption, distribution, metabolism, and excretion in the body?
Have the pharmacodynamic studies to evaluate the therapeutic effects, mechanisms of action and dose-response relationships of drugs been carried out?
Where is the evidence for possible adverse reactions and toxic effects, including acute toxicity, chronic toxicity, reproductive toxicity, and genotoxicity, which will help determine the safety and efficacy of the drug?
But you see, this is not mentioned in the instructions for the Xiaoer Chaigui Antipyretic Granules. It is estimated that these pharmaceutical companies may not necessarily do the research, because research costs money and the results may not be satisfactory.
This is also the reason why our traditional Chinese medicines are difficult to export and enter the international market. Without these studies, foreigners will not recognize your medicine as safe, and you will not be able to earn their money.
Dean Xiang seemed to be thinking about something, lit a cigarette, and prepared to listen to Lin Sanqi continue.
Lin Sanqi retrieved some pediatric medication from the tablet:
"President, please look at these pediatric medications. The main ingredients for reducing fever are ibuprofen and acetaminophen.
But there are many problems with pediatric medications now, such as ibuprofen.
It is a nonsteroidal anti-inflammatory drug, mainly used to relieve pain and reduce inflammation. However, this drug is highly toxic to the liver and kidney function of children, especially infants, and may also cause thrombocytopenia and coagulation disorders.
Another example is the commonly used medicine for children's colds, Paracetamol and Phenylephrine Granules. There are many reasons why pediatric departments do not recommend Paracetamol and Phenylephrine Granules for children, including the risk of skin rashes, gastrointestinal reactions, liver and kidney damage, and possible overdose of drug ingredients.
Then this one is not recommended, and that one is toxic. Does that mean there is no medicine to use when our children catch a cold or have a fever?
But if our pediatric Chai Gui is thoroughly researched and meets the needs of modern medicine, and is a natural raw material extracted from plants, wouldn't it have fewer side effects and better efficacy? Could it be promoted globally?
If that day really comes and Xiaoer Chaigui becomes the world's leading children's cold medicine, the market for this drug alone will be worth at least tens of billions of dollars. How can pharmaceutical companies not make a fortune? "
Dean Xiang laughed out loud when he heard this:
"I understand, I understand. It's just like artemisinin is extracted from Artemisia annua; aspirin is made from willow bark; ephedrine is extracted from ephedra; and the flu drug Tamiflu is extracted from star anise.
Xiaoqi, you have good vision. According to the latest edition of the Chinese Materia Medica, there are 8,980 kinds of Chinese medicine. If you include other medicines used by ethnic minorities, the latest statistics put the number at around 12,800.
This is a huge treasure trove, containing so much wealth, which requires us to find them, study them, and ultimately use them. Thinking about it this way, it shows that our traditional Chinese medicine has great potential."
Lin Sanqi nodded, "So Chinese medicine must also make progress and keep up with modern medicine. We must not stand still." (End of this chapter)
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