Shen Guoming listened for a long time, and at this time he couldn’t help it:
"What exactly is this cephalexin you're talking about? We only know it's an antibacterial drug, but what are its effects and significance?"
Lin Sanqi said embarrassedly:
"Oh, I got off topic. The cephalexin I mentioned can actually be thought of as an upgraded version of penicillin. It has almost the same antibacterial spectrum as penicillin, but it's more potent and more effective. Look everyone, I already have a finished product."
After saying that, Lin Sanqi asked his secretary to open a cardboard box next to his feet and take out the capsules inside.
In the early 1960s, there were no oral antibiotics.
(In real history, it was not until 1968 that the first oral antibiotic, cephalexin, was launched overseas.)
Sulfonamides were powders packaged in paper bags, which was quite primitive. Penicillin, on the other hand, was an injection and required refrigeration for transportation, making administration very inconvenient.
The medicine that everyone got at this time was packaged in a plastic board and sealed. Just by looking at the packaging, everyone knew that a high-tech product had arrived.
Lin Sanqi then continued:
"This oral cephalosporin has better efficacy and is convenient for patients to use. In the future, patients with infectious diseases do not need to go to the hospital. They can just take a few pills at home. What do you think of this convenient method?
Similarly, I took out this medicine that is more in line with our national conditions.
There are few hospitals in China now, even fewer doctors, and even fewer nurses who are specialized in giving injections. And even if we have syringes, how to sterilize them is a big problem.
I went to Shaanxi Province for an inspection before, and found that the provincial hospitals there also used iron pots, put used glass syringes and metal needles in them, boiled them for a while, and then continued to use them. They were reluctant to even soak them in alcohol.
I know that this is an action that the hospital has to take, but everyone should know that irregular disinfection will aggravate the cross-infection of various blood-borne infectious diseases, such as hepatitis, which is the most common, and some sexually transmitted diseases.
Therefore, we should remember a principle in the future: antibiotics should be used as little as possible and should not be abused. At the same time, oral administration should be avoided as much as possible to facilitate drug administration.
Imagine a patient comes to you in the future and you discover they have pneumonia or some other infection. Wouldn't it be more convenient and efficient to give them a few tablets of medicine and have them take it orally at regular intervals?
Shen Qiushui is a clinical doctor, and his eyes lit up when he heard this:
"Yes, it is not only more convenient to use, but also easy to carry. For example, I used to work in Yunnan, where there are mountains everywhere. It is very inconvenient for ordinary people, including the troops stationed in remote areas, to see a doctor.
We doctors make regular rounds, but only once a month at most. For many patients, one treatment is not enough. When the doctor leaves, they can only wait to die, because only professional doctors and nurses know how to give injections.
Now that we have this oral medication, it is possible to administer the drug according to the course of treatment.
Take this plate of cefuroxime. It says to take one or two pills twice a day. Even if the course of treatment is five days, going to the hospital for injections five days in a row was previously out of the question for ordinary people, unless they had a large family.
Now that we have this medicine, as a doctor, I can give 10 pills at a time, a five-day supply, so that patients can recover more completely. The increased chance of recovery means a significant reduction in mortality, which is completely in line with our current national conditions. It's great."
Everyone in the conference room began to talk about it, obviously realizing the great significance of the emergence of oral cephalexin.
At the same time, it also solves the harsh conditions during penicillin transportation, such as the need for low-temperature refrigeration and maintaining stability within 24 hours.
At this time, there are not even a few refrigerators in the country, so it is even more impossible to provide cold chain transport vehicles.
This is also the reason why penicillin is so expensive. It is hard for modern people to imagine that a bottle of penicillin requires a small yellow croaker, and in inland areas it even requires a large yellow croaker, and yet there is still no demand for it.
It also explains why during the War of Resistance Against Japanese Aggression, those injured anti-Japanese officers had to risk going to Shanghai for treatment, and then were betrayed by traitors, arrested, etc.
Do you really think these soldiers are stupid? Don't they know that going to the Japanese headquarters is extremely dangerous?
But they had no choice but to go to big cities to save their lives, because antibacterial drugs such as penicillin were difficult to transport to the rear areas.
Lin Sanqi asked Secretary Bai to distribute two more boxes of medicine to everyone:
"What everyone has in their hands now is a tablet called moxifloxacin and a tablet called azithromycin.
Why do we need to use these two relatively narrow-spectrum antibiotics when we already have broad-spectrum antibiotics like cephalosporins? This is because these two drugs have their irreplaceable functions.
For example, the antibacterial spectrum of azithromycin is different from that of cephalosporin and penicillin. For example, cephalosporin and penicillin cannot cover mycoplasma and chlamydia.
To give a very simple example, a patient has pneumonia, but not all pneumonia-causing bacteria are effective against cephalosporins. For example, viral pneumonia, mycoplasma pneumonia, etc., the efficacy is poor.
So at this time we have to use azithromycin, prescribe the right medicine for the disease, and recovery will be quick.
This is also one of the research contents of Professor Chai and his team. It does not mean that any disease can be killed with cephalosporin or penicillin. It is not like that.
Often, depending on what bacteria you are infected with, I will choose to use an antibiotic. This is the most scientific and effective clinical treatment.
As for the moxifloxacin in everyone's hands, its effect is even more powerful.
In a sense, moxifloxacin, like cephalosporin, is a broad-spectrum antibiotic that can cure any disease and kill any bacteria, but there are still big differences between the two.
Cephalosporin antibiotics have good antibacterial effects on both Gram-positive and Gram-negative bacteria.
Moxifloxacin is a broad-spectrum antibiotic that has certain antibacterial activity against some atypical pathogens, such as mycoplasma, chlamydia and Legionella.
It also has good antibacterial activity against anaerobic bacteria, so moxifloxacin is more effective for urinary tract infections, intestinal infections, etc.
In addition, moxifloxacin can also be used for our mainstay, anti-tuberculosis treatment, especially for those refractory and stubborn pulmonary tuberculosis.
President Jia, our anti-tuberculosis treatment cure rate is currently around 94%. If we add our traditional Chinese medicine and moxifloxacin, this cure rate can be increased by at least another 3 percentage points."
Jia Xuezhen replied with a smile:
"Director Lin has also provided us with bullets to target tuberculosis bacteria. Our clinicians now have enough information to kill the enemy and become the hospital with the highest tuberculosis cure rate in the world."
Lin Sanqi nodded and reminded:
"Tuberculosis treatment has been carried out abroad, and the 94% cure rate can almost solve the problem for the vast majority of patients. Therefore, our Baoan International Hospital must operate in a differentiated manner.
For example, if other hospitals can't treat difficult-to-treat, stubborn tuberculosis, we can. That means we have no shortage of patients. If patients with difficult-to-treat tuberculosis from all over the world come to us, we'll be rich.
Furthermore, these difficult-to-treat tuberculosis patients often develop drug resistance due to excessive wealth and comfortable living conditions, or develop multiple diseases due to disordered personal lives. These people have plenty of money, so we're ripping them off."
Hehehe~~~~
Everyone in the conference room chuckled.
Lin Sanqi's positioning standard for Bao'an International Hospital is to make it a profitable hospital that only accepts foreign patients and patients from Hong Kong and Macao and operates completely in a market-oriented manner. This will definitely help it earn more foreign exchange.
The Bao'an County People's Hospital, headed by Shen Qiu Shui, mainly treats patients from the mainland and is positioned as a low-cost, welfare-oriented hospital.
Shen Guoming said at this time:
"So what are the prices of these three antibiotics? If we want to mass-produce them, we have to consider the cost. If they are too expensive, ordinary people in China will still not be able to afford them."
Lin Sanqi blushed because he had previously talked to Wang Muye, the boss of Kenfu Pharmaceutical, for a long time about how you get what you pay for.
But when it came time to purchase, he asked for the cheapest raw materials, choosing two million per ton.
If he hadn't emphasized that this was exported to Africa, the upright Shandong man would have thought that he, a southerner, was hypocritical, saying one thing in front of others and another behind their backs.
"I have already obtained 20 tons of APIs, which is enough for now, and the cost is within my budget.
But since several professors are here, I have something to warn you about... (End of this chapter)
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