I am the Lord in the World of Mist

When the 'Heavenly Dog' devoured the sun, the apocalypse descended. Xu Zhi, a young girl with a heart condition, was cruelly abandoned by her parents in a dead city.

Countless mutated species and monsters were born from this dead city. Humanity expended immense effort to resist the invasion of these foreign species, and the city was sealed off, completely becoming a "Forbidden Zone for the Living".

Unbeknownst to anyone, in this city that had become a nest of monsters, a young girl quietly sat in a wheelchair, playing on a suddenly appearing game console.

Every time she successfully cultivated another powerful dependant in the game, the black mist shrouding the entire city would surge. One by one, the mutated monsters who had bowed to her in the game, calling her "Mother", continuously emerged from the mist, taking control of the entire city.

When humanity from the outside world finally prepared to explore this city full of death and danger, little did they know that a frail young girl had already become the deity of all monsters in the forbidden zone!

P.S.: No romance (CP). There are a significant number of female supporting characters, and the protagonist leans towards chaotic neutral.