However, Orochimaru had enough time and could wait, and Mizuki had no intention of controlling Orochimaru forever.

"If this is considered a punishment for my failure, it is appropriate. Fortunately, Mitsuki should not be affected. Besides, staying by your side may bring unexpected gains..."

"You are quite open-minded!"

Yusuke and Shin, who had been prepared on the side, took care of Mizuki who was lying on the test table, and began to prepare for the operation to transplant Uchiha Shisui's Mangekyō Sharingan.

"You're going to use Kotoamatsukami yourself? I thought you were going to have your clone transplant the Mangekyō Sharingan!"

"Other gods are special. If something goes wrong, it will be troublesome."

“That’s a good reason!”

Orochimaru nodded indifferently and turned to look around at some experimental specimens that Mizuki had collected.

"Researchers who are obsessed with biotechnology can't help but conduct human experiments, and even tamper with themselves. But you seem a little anxious now. Could it be that the fateful moment you predicted is approaching? I guess this is the only possibility."

Although Orochimaru and Mizuki are both characters who are cruel to others and even crueler to themselves, there is one thing they both adopted: they both adopted the same strategy.

Although they make extensive use of the power inherited from ancient times, including bloodline limits, they rarely transplant it directly into themselves. This is not because they have any physical or spiritual cleanliness obsession, but out of safety considerations.

The more powerful the force, the greater the harm it will bring when its compatibility is poor. The two who have studied many biological phenomena understand that the genetic gene chain of the creatures in the ninja world is very fragile, and the mutual interference between matter, energy and spirit is extremely obvious. The transplanted Sharingan. Especially the Mangekyō Sharingan, even if it is removed afterwards, is absolutely different from the body that has never been transplanted. Otherwise, why would Nagato have the characteristics of the Samsara Eye after being resurrected by the Impure World Reincarnation.

"It's just for a short time, it shouldn't be a big problem!"

This unexpected bloodline limit imposed on one's body has a greater impact on the body than being placed under high-intensity nuclear radiation.

Chakra is the culprit that causes all this. Take Kakashi Hatake as an example. The Kakashi more than ten years ago and the Kakashi now who has adapted to the Mangekyō Sharingan, after so much passive modulation of chakra, their physical conditions have changed a lot. If Kakashi dies now and is then resurrected by the Impure World Reincarnation, it is very likely that his left eye will also have the Mangekyō Sharingan.

This transformation does not mean that the blood of the Uchiha family and the Hatake family have merged, but the positive enhancement effect of Kakashi's own chakra, which makes his body more adapted to Uchiha Obito's Mangekyō Sharingan. If Kakashi has descendants, although they still have no blood relationship with the Uchiha family, they will definitely not find it as difficult to use the Sharingan as Kakashi.

Most of these changes are harmless, but sometimes they are not necessarily. For example, the Inuzuka family's sense of smell was greatly enhanced by performing animal-mimicking ninjutsu with their ninja dogs. This may be a good thing for the Inuzuka family, but Mizuki does not want such a specialty.

The more powerful the bloodline limit, the more obvious the mutation it brings. If it is not necessary, a researcher who is truly proficient in biotechnology will not add bloodline limits to his body at will. Like Kabuto in the original work, who injected countless bloodline limit cells into his body and made himself neither valuable nor inferior, this is a lesson for us. Although Orochimaru's path is to collect resources and evolve himself, it is definitely not this kind of uncontrolled and reckless behavior.

"Every researcher will pay attention to maintaining their own purity, not only for safety, but also to prevent their own will from being distorted!"

The one who is most affected by the alien chakra is actually the jinchūriki. Otherwise, why would the jinchūriki who was resurrected by the Impure World Reincarnation be able to accept the power of the tailed beast chakra so easily?

Of course, the fairy mode is no less serious. If you cannot isolate yourself from the invasion of natural energy, you will either become a madman who loses yourself, or become a part of natural phenomena, like the Jūgo clan or the stone frog of Myōboku Mountain.

Orochimaru seemed to have expected this.

"For most non-Uchiha people who have had their Sharingan transplanted, their mental fluctuations will become much larger. I'm sure you've discovered that second-hand goods that are not genuine are not easy to use after all."

"What a harsh thing to say!"

Mizuki curled his lips. Does Orochimaru need to teach him this?

The Sharingan is not only a powerful tool for materializing spiritual power, but also a magnifying glass with considerable amplification.

Sunlight can be focused through a magnifying glass to get a higher temperature, but if it is not operated properly, the focus will be on yourself, which will not be a pleasant experience.

If the mind of an ordinary person is compared to a large lake, a Sharingan is like a hole in the dam, allowing the originally calm lake water to vent. If it is not properly controlled, accidents are likely to occur. If the dam blocking the lake is broken, it will be no small matter.

And now, it is estimated that Kabuto Yakushi has dug the two big holes of his own with the Sage Mode and the Mangekyō Sharingan, and his mental space has long been flooded.

Mizuki transplanted Uchiha Shisui's Mangekyō Sharingan into his own body, so he would naturally be more careful. He would also take strict precautions against his own body. Having finally escaped from his limited lifespan and the invasion of natural energy, Mizuki would never add any uncontrollable constraints to his body again.

Mizuki, who had many transplant experiences, was of course no stranger to this. Not long after, the Mangekyō Sharingan was successfully transplanted.

Mizuki, with his eyes blindfolded, quietly felt how to use the power of the Mangekyō Sharingan.

"Is this the coveted Mangekyō Sharingan? It doesn't seem to have anything special about it, except that the chakra consumption is astonishing..."

If it were an ordinary person, with the Mangekyō Sharingan that couldn't be turned off, it would be good enough if he could fight well, let alone use it.

"If anyone else said this, I would just think it was just stupid talk, but it's you..."

Orochimaru had no idea that he would be controlled by someone else. He calmly watched Mizuki adapt to the power of the Mangekyō Sharingan.

Fortunately, there are various medicines, and I am also a good medical ninja. This kind of surgical injury will be completely healed in a while. The main trouble is how to control the power of the Mangekyō Sharingan.

Mizuki took off the cloth covering his eyes with some impatience. After sensing the movements around him, he slowly opened his eyes, revealing a pair of Mangekyō Sharingan.